Himadri Sharma, Niti Sharma, Seong Soo A. An
Neuroprotective Evaluation of Murraya Carbazoles: In Vitro and Docking Insights into Their Anti-AChE and Anti-Aβ Activities.
PubMed 30(15)
Himadri Sharma, Ph.D.
조교수
소개
Himadri Sharma는 향신료, 약용식물, 균류에서 얻은 천연 화합물을 알츠하이머병 치료 후보로 연구합니다. 2023년부터 후추, 정향, 아즈와인(Trachyspermum ammi), 딜, 카다멈, 회향, 동충하초(Cordyceps), 머라야(Murraya) 유래 카바졸 알칼로이드를 대상으로 아세틸콜린에스테라아제 억제, 아밀로이드-β 올리고머 및 섬유 형성 억제, 산화 스트레스로부터 SH-SY5Y 신경세포를 보호하는 효과를 측정했습니다.
또한 알츠하이머병 연구용 포유류 모델, 베바시주맙과 바이오시밀러를 이용한 VEGF/VEGFR 표적 암 치료에 관한 종설을 썼으며, 알츠하이머병 혈액 바이오마커 종설에도 참여했습니다.
연구 관심 분야
- 신경보호 천연물
연구 분야
제1저자 논문
논문 10편
연구실 구성원의 ORCID 기록에서 자동으로 갱신됩니다.
2025
2024
Himadri Sharma, Hye-Won Yang, Niti Sharma, Seong Soo A. An
Multivalent Neuroprotective Activity of Elettaria cardamomum (Cardamom) and Foeniculum vulgare (Fennel) in H2O2-Induced Oxidative Stress in SH-SY5Y Cells and Acellular Assays
Pharmaceuticals 18(1):2
Himadri Sharma, Hye-Won Yang, Niti Sharma, Seong Soo A. An
Neuroprotection by Anethum graveolens (Dill) Seeds and Its Phytocompounds in SH-SY5Y Neuroblastoma Cell Lines and Acellular Assays
International Journal of Molecular Sciences 25(13):7104
Himadri Sharma, Seong Soo A. An
VEGF/VEGFR Inhibition for Cancer Treatment using Bevacizumab and its Biosimilars: A review
KSBB Journal 39(2):41–53
Himadri Sharma
In vitro evaluation of neuroprotective effect of Anethum graveolens and its bioactives in H 2 O 2 -induced oxidative stress model of SH-SY5Y and biochemical studies
Alzheimer's Association International Conference
2023
Himadri Sharma, Hye-Won Yang, Niti Sharma, Seong Soo A. An
Trachyspermum ammi Bioactives Promote Neuroprotection by Inhibiting Acetylcholinesterase, Aβ-Oligomerization/Fibrilization, and Mitigating Oxidative Stress In Vitro
Antioxidants 13(1):9
Himadri Sharma, Niti Sharma, Seong Soo A. An
Unique Bioactives from Zombie Fungus (Cordyceps) as Promising Multitargeted Neuroprotective Agents
Nutrients 16(1):102
Himadri Sharma, Keun‐A Chang, John Hulme, Seong Soo A. An
Mammalian Models in Alzheimer’s Research: An Update
Cells 12(20):2459
Himadri Sharma, Niti Sharma, Seong Soo A. An
Black Pepper (Piper nigrum) Alleviates Oxidative Stress, Exerts Potential Anti-Glycation and Anti-AChE Activity: A Multitargeting Neuroprotective Agent against Neurodegenerative Diseases
Antioxidants 12(5):1089
Himadri Sharma, Danyeong Kim, Kyu Hwan Shim, Niti Sharma, Seong Soo A. An
Multi-Targeting Neuroprotective Effects of Syzygium aromaticum Bud Extracts and Their Key Phytocompounds against Neurodegenerative Diseases
International Journal of Molecular Sciences 24(9):8148