Niti Sharma, Seong Soo A. An
Small-Molecule NANT Therapeutics Targeting the Brain–Immune Axis in Alzheimer’s Disease: Mechanisms, Clinical Progress, and Translational Challenges
Molecules 31(18):3274
Niti Sharma, Ph.D.
조교수
소개
Niti Sharma는 2021년부터 가천대학교 바이오나노연구원 조교수로 재직하고 있습니다. 약용식물과 향신료에서 알츠하이머병의 신경세포를 보호할 수 있는 화합물을 찾고, 아세틸콜린에스테라아제 억제, 아밀로이드-β 응집 억제, 산화 스트레스 완화 효과를 시험합니다. 최근에는 혈액 바이오마커와 혈액-뇌 장벽, 치매 위험과 관련된 약물 및 환경 화학물질, 나노입자 규제 동향에 관한 종설을 발표했습니다.
2001년 인도 CCS 하리아나 농업대학교(CCS Haryana Agricultural University)에서 생화학 박사 학위를 받았습니다. 이후 공주대학교(2002–2003), 전북대학교(2003–2004), 교토약과대학(2004–2005)에서 연구했고, 충남대학교에서 의약화학 분야 박사후연구원(2010–2014)으로 일했으며, 인도 파탄잘리 연구재단(Patanjali Research Foundation)에서 허브 제제와 식물 추출물을 연구했습니다.
연구 관심 분야
- 신경보호 식물화합물
연구 분야
학력
| 학위 | 기관 | 연도 |
|---|---|---|
| Ph.D., Biochemistry | CCS Haryana Agricultural University, India | 2001 |
제1저자 논문
논문 18편
연구실 구성원의 ORCID 기록에서 자동으로 갱신됩니다.
2026
Niti Sharma, Sung-Kwang Shin, Seong Soo A. An, Meyoung-Kon Jerry Kim
Trends in nanotechnology product registration and media coverage in South Korea across the COVID-19 era
Molecular & Cellular Toxicology
Niti Sharma, Seong Soo A. An
Microglial Dysfunction Induced by C9ORF72 Dipeptide Repeat Proteins: Biomarker and Therapeutic Perspectives
International Journal of Molecular Sciences 27(12):5537
Niti Sharma, Seong Soo A. An
Multitarget Actions of Pentacyclic Triterpenic Acids in Alzheimer’s Disease: Mechanistic Insights
Molecules 31(12):2018
2025
Niti Sharma, Danyeong Kim, Himadri Sharma, Moon Il Kim, Hyon Lee, Minju Kim, Nayoung Ryoo, Min Ju Kang, Jung‐Min Pyun, Young Ho Park, Jisun Ryu, Hyun Jung Oh, Hyun‐Sik Yang, Hang‐Rai Kim, Geon Ha Kim, Sangwon Han, YoungSoon Yang, Young Chul Youn, Charlotte Elisabeth Teunissen, Henrik Zetterberg, Philip Scheltens, Seong Soo A. An, Young-Bum Kim, Sang-Yun Kim
Bridging the barrier: insights into blood biomarkers and therapeutic strategies targeting choroid plexus and BBB dysfunction in alzheimer’s disease
Biomarker Research 13(1):116
Niti Sharma, Seong Soo A. An
Soil to Synapse: Molecular Insights into the Neurotoxicity of Common Gardening Chemicals in Alzheimer’s and Parkinson’s Disease
International Journal of Molecular Sciences 26(13):6468
Niti Sharma, Danyeong Kim, Himadri Sharma, Moon Il Kim, Hyon Lee, Minju Kim, Nayoung Ryoo, Min Ju Kang, Jung‐Min Pyun, Young Ho Park, Jisun Ryu, Hyun Jung Oh, Hyun‐Sik Yang, Hang‐Rai Kim, Geon Ha Kim, Sangwon Han, YoungSoon Yang, Young Chul Youn, Charlotte Elisabeth Teunissen, Henrik Zetterberg, Philip Scheltens, Seong Soo A. An, Young‐Bum Kim, Sang-Yun Kim
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review
Alzheimer s & Dementia 21(7):e70475
2024
2021
Niti Sharma, Mario A. Tan, Seong Soo A. An
Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
International Journal of Molecular Sciences 22(22):12255
Niti Sharma, Mario A. Tan, Seong Soo A. An
Mechanistic Aspects of Apiaceae Family Spices in Ameliorating Alzheimer’s Disease
Antioxidants 10(10):1571
2014
Niti Sharma, P Sharma, ND Jasuja, SC Joshi
Ameliorative efficiency of Coriandrum sativum seed extract on atherosclerosis and oxidative stress in male albino hyperlipidemic rabbits
Res. J. Pharm. Biol. Chem. Sci 5:26-39
2008
Niti Sharma
Recombinant proteins in therapeutics
Pariprashna 3(1):59-61
2006
Niti Sharma, Tae-Geum Kim, Moon‐Sik Yang
Production and secretion of human interleukin-18 in transgenic tobacco cell suspension culture
Biotechnology and Bioprocess Engineering 11(2):154–159
2005
2004
Niti Sharma, Seung-Moon Park, Taeho Kwon, Dae‐Hyuk Kim, Moon‐Sik Yang
A simple purification procedure of biologically active recombinant human granulocyte macrophage colony stimulating factor (hGM-CSF) secreted in rice cell suspension culture
Biotechnology and Bioprocess Engineering 9(6):423–427
2003
Niti Sharma, Archana Phutela, Sarla Popli Malhotra, Randhir Kumar Singh
Lipid Composition of in vitro Developing Seeds of Brassica campestris L.
Biologia Plantarum 46(4):581–584
Niti Sharma, ARCHANA ARCHANA, Sarla Popli Malhotra, Randhir Kumar Singh
A simple method for in vivo labelling of lipid fractions in developing seeds of Brassica campestris L
Acta Physiologiae Plantarum 25(1):77–82