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Blood Pathology Lab혈액병리 연구실

Danyeong Kim

Ph.D. Student

Biography

Danyeong Kim studies how gene mutations found in patients with Alzheimer's disease, Parkinson's disease and related disorders change protein function. This work has used CRISPR/Cas9-edited cells carrying APP Val604Met and PSEN1 Gly417Ala, cell models of the TREM2 variants T44A and L15Q and their effect on amyloid-β, and the Parkinson's disease mutation ATP10B R303W.

Other projects use the Timed Up and Go test to measure gait and balance in Parkinson's disease, measure acetylcholinesterase activity in blood exosomes, and test compounds that block amyloid-β oligomer formation.

Research interests

  • Mutation functional studies

Research areas

First-author publications

12 publications

Updated automatically from the lab's ORCID records.

2026

  1. Danyeong Kim, Minji Son, Jeanhong Jeon, Da-Eun Jeong, Hyun Kyung Yi, Min Ju Kang

    Quantitative Analysis of Timed Up and Go Metrics Across Parkinson’s Disease Severity and Their Clinical Correlations

    Diagnostics 16(14):2283

    DOIPubMed

  2. Danyeong Kim, Heewon Bae, Kyu Hwan Shim, Hyewon Yang, Da-Eun Jeong, Min Ju Kang, Seong Soo A. An

    A novel TREM2 L15Q in signal peptide domain and its influence on Aβ pathogenicity

    npj Dementia 2(1)

    DOIPDF

2025

  1. Danyeong Kim, Da‐Eun Jeong, Yunseo Gong, Hongjae Ahn, Min Ju Kang, Seong Soo A. An

    Characterization of ATP10B R303W as a Novel Pathogenic Mutation in Parkinson's Disease

    Alzheimer s & Dementia 21(S1):e097660

    DOIPubMedPDF

  2. Danyeong Kim, KyuHwan Shim, Jinho Kim, Geon Ko, Mario A. Tan, Keun-A Chang, Seong Soo A. An

    Potential anti-amyloid beta oligomerization effects of PD166793 in Alzheimer's disease

    Experimental Neurology 396:115504

    DOIPubMed

  3. Danyeong Kim, Da-Eun Jeong, Hyunkyung Yi, Min Ju Kang

    Gait Patterns and Balance Impairment in Parkinson’s Disease With Correlation to Disease Severity

    Dementia and Neurocognitive Disorders 24(4):259

    DOIPubMedPDF

2024

  1. Danyeong Kim, Kyu Hwan Shim, Yunseo Gong, Hye-Won Yang, Min Ju Kang, Seong Soo A. An

    Examining pathology of Alzheimer’s disease via clusterin and Aβ interaction

    Alzheimer s & Dementia 20(S1):e087898

    DOIPubMedPDF

2023

  1. Danyeong Kim, Nayoung Ryoo, Young Ho Park, Eva Bagyinszky, Seong Soo A. An, SangYun Kim

    A Novel Mutation in Sacsin, p.Val1335IIe, May Cause Late-Onset Sacsinopathy Due to Haploinsufficiency

    Current Issues in Molecular Biology 45(12):9917–9925

    DOIPubMedPDF

  2. Danyeong Kim, Kyu Hwan Shim, Hye-Won Yang, Heewon Bae, Min Ju Kang, Seunghwan Shin, Jongsung Kim, Kyusik Yun, Chang‐Hyun Jang, Seong Soo A. An

    Pathogenic characteristics of genetically modified cells with TREM2 T44A mutation

    Alzheimer s & Dementia 19(S13)

    DOIPDF

2022

  1. Danyeong Kim, Kyu Hwan Shim, Eva Bagyinszky, Giau Van Vo, Min Ju Kang, Vorapun Senanarong, Chanin Limwongse, Seunghwan Shin, SoonPyo Jeong, Jongsung Kim, Young Ho Park, Young Chul Youn, SangYun Kim, Seong Soo A. An

    Characteristics of β‐secretase activity on APP‐V604M and APP‐V669L

    Alzheimer s & Dementia 18(S3)

    DOI

  2. Danyeong Kim, Kyu Hwan Shim, Eva Bagyinszky, Seong Soo A. An

    Prion Mutations in Republic of Republic of Korea, China, and Japan

    International Journal of Molecular Sciences 24(1):625

    DOIPubMedPDF

2021

  1. Danyeong Kim, Giau Van Vo, Eva Bagyinszky, Seong Soo A. An

    PSEN1 Gly417Ala by CRISPR/Cas9 in functional pathogenicity

    Alzheimer s & Dementia 17(S3)

    DOI

2020

  1. Danyeong Kim, KyuHwan Shim, Giau Van Vo, Eva Bagyinszky, Seong Soo A. An

    Functional characterizations of APP VAL604MET by CRISPR/CAS9

    Alzheimer s & Dementia 16(S2)

    DOIPDF